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Results: 1
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Blocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson's disease.
Rebeka Popovic
,
Amrita Mukherjee
,
Nuno Santos Leal
,
Lydia Morris
,
Yizhou Yu
,
Samantha H Y Loh
,
L Miguel Martins
Apr 17, 2023
Parkinson's disease (PD) is characterised by selective death of dopaminergic (DA) neurons in the midbrain and motor function impairment. Gastrointestinal issues often precede motor deficits in PD, indicating that the gut-brain...
Animals
Drosophila
Drosophila melanogaster
Parkinson Disease
Drosophila Proteins
Unfolded Protein Response
Protein Serine-Threonine Kinases
Published by:
Cell Death & Disease